A multisystem inflammatory disease like Psoriasis requires constant attention tocontrol the inflammation and prevent frequent flare ups. If mismanaged, psoriasis can cause a range of health complications such as hypertension, diabetes, kidney disease, skin problems and cardiovascular diseases. Correct treatment can not only alleviate the symptoms but also treat persisting skin problems. With treatment adherence, patients can get clearer skin, which can further motivate them in long term management of Psoriasis. Therefore, regular communication is fundamental for the right treatment, advice, and information. For psoriasis management, there are several safe and effective therapy options available today. Determining the right treatment method depends on several factors including the patient disease severity, risk of comorbidities and susceptibility to various risk factors. Advanced therapies, including biologics, have added to the options of therapeutic treatment of moderate to severe Psoriasis. They are highly effective in successfully disrupting the disease cycle. It has a favorable risk reward profile and is well tolerated by patients. This has proven to improve acceptance and facilitate better adherence. Psoriasis patients need holistic treatment and support, right from the initial stages. We need an understanding of the barriers to treatment adherence and accessible information for both patients and clinicians. There is a clear need in India for multi stakeholder interventions, uniting patient groups, specialists including dermatologists and rheumatologists, the government, industry bodies and private players towards establishing a patient centric model of care while driving emotional and social support. In early February this year, the National Payments Corporation of India NPCI in a proud revelation announced that our neighbor, Nepal would be the first foreign country to adopt India UPI Unified Payments Interface system.