Multidetector computed tomography of the thorax and upper abdomen demonstrates patchy ground-glass opacities with areas of interlobular septal thickening and subpleural reticulation. No cavitary lesion or bronchiectatic change identified. Cardiothoracic ratio within normal limits with preserved mediastinal contours and no evidence of hilar lymphadenopathy. The aortic arch and major branches show normal luminal opacification without aneurysmal dilatation or dissection flap. Pericardium is intact with no pericardial effusion. Evaluation of hepatic parenchyma reveals mild heterogeneity with focal hypodense lesion in segment VIII showing peripheral nodular enhancement and centripetal fill-in on delayed phase, consistent with hemangioma. Gallbladder shows multiple laminated calculi with mild mural thickening, suggestive of chronic cholecystitis. Pancreatic duct is not dilated and peripancreatic fat planes are preserved. Both kidneys demonstrate preserved cortical thickness with no hydronephrosis or nephrolithiasis. Urinary bladder shows smooth contour and homogeneous wall enhancement. No free intraperitoneal air or ascites identified. Osseous structures reveal diffuse osteopenia with marginal osteophyte formation and endplate sclerosis at multiple levels. There is mild anterolisthesis of L4 over L5 with associated facet joint arthropathy and ligamentum flavum hypertrophy, resulting in moderate spinal canal stenosis. Cervical vertebral bodies demonstrate straightening of the normal lordotic curvature with multilevel spondylotic changes. Neural foramina show mild narrowing bilaterally. Brain MRI reveals diffuse cortical atrophy with prominent sulci and ventriculomegaly disproportionate to age. Periventricular and deep white-matter hyperintensities noted on T2-weighted and FLAIR sequences, likely representing chronic microangiopathic ischemic changes. No diffusion restriction or susceptibility artifact detected. Pituitary gland, optic chiasma, and cerebellopontine angles appear unremarkable. Major intracranial vessels show normal flow voids. Paranasal sinuses are clear. No extra-axial collection or mass effect observed. Overall impression: mild chronic microvascular ischemic changes with age-related cerebral atrophy, degenerative spondylotic alterations of the cervical and lumbar spine, and chronic cholecystitis with hepatic hemangioma.